How Free Radicals Affect the Aging Process
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How Free Radicals Affect the Aging Process

November 02, 2020

It is well known that as we grow older the body begins to slow down. However, for many, it's not clear why this happens or what can be done to prevent it. One of the greatest contributors of age-related dysfunction including declining heart health, reduced cognitive function, and muscular atrophy are free radicals. When in excess, these promoters of oxidative stress can negatively impact virtually every part of the body and hasten the aging process. Fortunately, there are methods of combating free radical-related oxidation to reduce the impact of aging.

Age Well is a supplement produced by HoltraCeuticals that is focused on improving the aging process and combating damage caused by free radicals as well as other contributors of aging. Age Well is formulated specifically to assist the genes responsible for regulating the body’s antioxidant systems, which improves the ability to combat oxidative stress. This is made possible because of powerful ingredients that provide impressive antioxidant benefits. The ingredients in Age Well have also been shown to reduce the risk of major health issues such as heart disease, cognitive decay, and cancer.

Free Radicals, Oxidation, and Aging

A unifying factor of age-related illness and degeneration is damage caused by free radicals. Free radicals are unstable molecules that are missing an electron. The body naturally produces free radicals during natural bodily processes such as cellular reactions, food metabolization, and even breathing. It is expected that these processes produce a small number of free radicals. Maintaining a low level of free radicals is considered healthy. However, problems develop when the number of free radicals exceeds the number of antioxidants in the body. Poor nutrition, excessive exposure to toxins, and immune dysfunction can all contribute to reduced antioxidant levels and a higher prevalence of free radicals.

Free radicals attempt to steal electrons from other cells in order to complete their structure. When an electron is stolen, the victim of the theft becomes unstable which causes it to become unstable. Furthermore, the damaged cell also attempts to steal electrons from other cells resulting in a chain reaction and proliferation of free radicals. This disruption of cellular function can build over time and cause serious damage. Ultimately, free radicals harm the body by damaging DNA, cell membranes, fats stored in blood vessels, and enzymes. This damage is known as oxidation. Excessive oxidation can cause significant health issues and accelerate aging.

How Supplementing with Age Well Can Help

Deterring free radical damage requires maintaining an appropriate level of antioxidants. Antioxidants help combat free radicals by donating electrons and then safely decomposing. This decreases free radical activity without contributing to the problem. Supporting the body with Age Well, which contains a powerful collection of antioxidants including resveratrol, quercetin, pterostilbene, and others, can help restore antioxidant levels and combat free radical damage. High-quality ingredients in Age Well can help improve the aging process and overall wellness.


Resveratrol is a bioflavonoid antioxidant that is considered by many to be one of the best polyphenols for protecting against free radical damage. One of the major benefits of resveratrol is its regulatory effect on inflammation. Chronic inflammation can cause greater disruption of cellular activity, which can worsen symptoms of aging, damage immune function, and increase the risk of developing chronic conditions. Resveratrol reduces the impact of chronic inflammation and free radical damage by regulating the expression of specific enzymes that trigger inflammation and other chemical reactions.

As an antioxidant, resveratrol enters into mitochondrial nuclei to help repair free radical damage. This also supports mitochondrial respiration which supports cellular energy and activity. Furthermore, resveratrol regulates apoptosis, which encourages the destruction of harmful and potentially cancerous cells. Studies have found that resveratrol can trigger the destruction of activated T cells thereby limiting the growth and proliferation of tumors and cancerous cells.


Pterostilbene is an antioxidant derived from resveratrol and shares many similar benefits. According to a 2013 review published in the journal of Oxidative Medicine and Cellular Longevity, pterostilbene has anti-carcinogenic and anti-inflammatory properties, protects against neurological disease, supports cardiovascular health, suppresses diabetes, and combats free radical damage.

Although it is structurally similar to resveratrol, pterostilbene is more potent and bioavailable meaning that the body can more easily utilize it. Pterostilbene has a bioavailability near 80 percent while resveratrol is notably lower at 20 percent. Most acquire pterostilbene from vegetable and fruit sources. But, these powerful anti-aging substances can also be acquired through supplementing with a high-quality product such as Age Well.


Quercetin is a naturally occurring substance found in many antioxidant-rich foods such as broccoli, pomegranates, and various berries. Quercetin is a flavonoid antioxidant that is one of the most abundant in our diet. This is beneficial because quercetin actively fights free radical damage. Even though quercetin is often a prominent part of the diet, taking a supplement containing quercetin, such as Age Well, can further improve antioxidant function and suppress the effects of aging.

Flavonoid polyphenols like quercetin are best utilized for their ability to down-regulate inflammation. Quercetin is recognized for its powerful effect on immune function, limiting oxidative stress, and reducing inflammation caused by leukocytes and other inflammatory factors. In addition to combating free radical damage and oxidation, quercetin provides benefits such as:

  • Better inflammation regulation
  • Cancer prevention
  • Greater skin health
  • Improving allergic response
  • Pain relief
  • Supporting cardiovascular health

Protecting Your Future Through Effective Supplementation

Many believe that the symptoms of aging are inevitable and unavoidable. However, by properly supporting the body with a healthy lifestyle, balanced diet, and appropriate supplementation, the dreaded symptoms of aging can be significantly reduced. Powerful substances such as resveratrol, pterostilbene, and quercetin, provide impressive antioxidant benefits that combat free radical damage, improve immunity, and support healthy longevity. Incorporating these and other helpful anti-aging factors into your wellness regimen can be done by using HoltraCeuticals’ Age Well supplement. This robust formulation protects against the most common contributors of aging in the form of free radical damage and inflammation. Taking Age Well supports healthful aging and helps prevent the occurrence of age-related diseases such as heart disease, neurological atrophy, cancer, and chronic disease.


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